Webcast
The Medicines Company 1Q Earnings Call
Wednesday, April 23, 2008
at 8:30 AM ET
(1Q 2008 Fact Sheet)

 Webcast
The Medicines Company 4Q and Full Year 2007 Earnings Call
Wednesday, February 13, 2008
at 8:30 AM ET
(Full Year and 4Q Fact Sheet)

 Webcast
MEDICINES CO to Participate in the 26th Annual JP Morgan Healthcare Conference
Monday, January 7, 2008
at 4:30 PM Pacific Time

 Webcast
MEDICINES CO to Participate on Panel at RBC Capital Markets 2007 Healthcare Conference
Wednesday, December 12, 2007
at 4:30 PM ET

Released 5/5/08
Results Published in JACC Show Clinical Advantage of Switching to Angiomax from Heparin in Acute Coronary Syndrome Patients Undergoing Early Invasive Treatment

Released 4/30/08
The Medicines Company Announces Option Grants under NASDAQ Marketplace Rule 4350

Released 4/23/08
The Medicines Company Reports First Quarter 2008 Financial Results

Released 4/15/08
The Medicines Company Announces Option Grants Under NASDAQ Marketplace Rule 4350

Released 4/9/08
The Medicines Company to Announce First Quarter 2008 Financial Results on Wednesday, April 23, 2008